Hi Gregory - yes, I have a Members group that I granted +Read +Modify+Create etc.
I only have one Library as I am just building out the site and will add another Library with the same Group and access. My plan (so far) was to have a separate Library for my Quality Procedures that we only want a few people to have the ability to change.
If I used one library I suppose I could add a deny for my large group of Members against the sub-set of Quality doc's then add a grant to that same sub-set to a small "Quality" group...