What is the full stack trace of the error message when you try to start the profiler? That might give us a better idea of why it can't connect to Windchill. What version of Windchill are you using?
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What is the full stack trace of the error message when you try to start the profiler? That might give us a better idea of why it can't connect to Windchill. What version of Windchill are you using?